Friday, 6th February 31st Annual Lorne Proteomics Symposium 2026

The ZenoTOF 8600 system: from single cells to diverse proteomics applications.

Speaker: Denys Oliinyk

Organization: Max Planck Institute of Biochemistry (Mann Lab)

• From prevention to treatment: a proteomics-driven approach to transforming fungal disease management - Jennifer Geddes-McAlister
• Metaproteomics for uncovering drug-microbiome interactions - Daniel Figeys
• The Use of Structural Proteomics in the Analysis of Antimicrobial Resistance Mechanisms of Acinetobacter Baumannii - Aiden Brennan
• Proteomic Profiling of Klebsiella pneumoniae Under Infection-Mimicking Conditions Reveals Environment-Specific Adaptations - Breyer Woodland

• Simultaneous Measurement of the Proteome and Lipidome of Individual Cells - Leonard Foster
• Understanding host-microbiome interactions in early type 1 diabetes with stool proteomics - Emma Hamilton-Williams
• Bridging clinical ontologies and proteomics to overcome statistical limitations in rare disease research - Ericka Corazon Itang
• Integrating quantitative proteomics and PISA to identify molecular targets of novel anthelmintic compounds in the model parasitic nematode Haemonchus contortus - Tao Wang

• Constructing region-specific nuclear map of the heart - Seyed Sadegh Eslami
• Spatial proteomics to study immune cells driving inclusion body myositis - Kael Schoffer
• Secretome-Driven Modulation of CD8⁺ T Cell Function in the Pancreatic Tumour Microenvironment - Ragini Bhalla
• Copper intrauterine device (IUD) use associates with metaproteomic signatures of genital inflammation, altered epithelial barrier function, and microbial dysbiosis in South African women   - Nina Radzey
• Proteomic Signatures of Noise Damage: A Comparative Study in Rat Inner Ear and Systemic Fluids - Motahare Khorrami

• Differential Regulation of Cytoplasmic and Secreted Proteins in Staphylococcus aureus Under Host-Mimicking Conditions - Ching-Seng Ang
• Cellular Heterogeneity and Radiation Resistance in Diffuse Midline Glioma: A Single-Cell Perspective. - Dylan H Multari
• Lyophilization prior to homogenisation and extraction increases protein yield and enriches for membrane proteins in proteomic analysis of Gram-negative bacteria - Breyer Woodland
• Data-Independent acquisition for comprehensive immunopeptidome profiling on a modified Orbitrap Astral mass spectrometer - Joanne Ford
• Complementary proteomics approaches for identification of interacting partners and function of the malaria parasite regulatory protein Alba4 - Meghan E Zadow
• Leveraging advanced mass spectrometry technology with Orbitrap Astral Zoom MS for in depth immunopeptidome profiling - Tyren Dodgen
• Proteomics and O-Glycoproteomics – Comprehensive Profiling of Colorectal Cancer Patients in Stages I–IV - Mariusz G. Fleszar
• Defining the antigenic landscape of ewing sarcoma for HLA-dependent T-Cell therapy - Grace Huang
• Enabling reproducible integrative multi-omics analyses using the MultiScholaR R Shiny graphical user interface - C. Ruth Wang
• Vaginal metaproteomic and inflammatory profiles during pregnancy and relationships with birth outcomes - Jenna Wilson
• Cancer Testis Antigens are Potential Targets for Immunotherapy for the Prevention and Treatment of Relapsed and Metastatic Osteosarcoma - Mersedeh Shayan
• Radiation-Induced Proteome and Immunopeptidome Remodeling in H3K27M Diffuse Midline Glioma Cells - Nurfarhanah Syed Sulaiman
• The Proteomic Analyst Suites: A collection of easy-to-use interactive web applications to analyse and visualise proteomic datasets - Haijian Zhang
• Understanding Glycosylation Regulation: Impact of Flippase Modulations on Mediating O-glycan Toxicity Within Burkholderia cenocepacia - Tak To Duncan Ho
• Multi-dimensional Immunopeptidomic Analysis of Tumour, PBMC, and Plasma in Gliolastoma - Erwin Tanuwidjaya
• Proteomic Signatures of Lead Exposure and Adaptation in House Sparrows from Australian Mining Towns - Zeshan Ali
• Investigating The Molecular Interactions of Novel Proteins Driving Treatment Induced Neuroendocrine Prostate Cancer. - Hadeel Doehler
• PromarkerEndo: a blood-based proteomic test for endometriosis - Scott Bringans
• Benchmarking Plasma Proteomics Workflows: Balancing Depth, Reproducibility, and Pre-Analytical Bias on a timsTOF HT Platform - Susanne I Wudy
• PromarkerD performance across diverse populations for early detection of diabetes-related kidney disease - Richard Lipscombe
• Amino acid site preference and allotype-specific variation in glycosylation of class I immunopeptides - Joshua Fehring
• New tools for the antimalarial toolbox: novel proteomic approaches for drug target ID in malaria parasites - Joshua P Morrow
• From Chemistry to Clinic: Improved Cell Surface Proteomics Workflows for Target Discovery in Acute Myeloid Leukaemia (AML) - Vineet Vaibhav
• A Window of Opportunity: Liquid Biopsy Proteomics for Early Detection of Pancreatic Cancer - Laura F Dagley
• Influenza infection of lung epithelial cells expressing common HLA-I variants to define conserved influenza targets by immunopeptidomics - Ngoc Hong Le
• Using a proteogenomics approach to elucidate the protein isoforms correlating with chemoresistance in ovarian cancer - Atyuha Jain
• Multiplex Olink cytokine profiling of the wound environment in patients with hand infections reveals network of dynamic and highly expressed proinflammatory cytokines - An Qi Ngoh
• Proteomic characterisation of synergistic partners of the antimalarial drug, tafenoquine - Janelle L Hancock
• A data-driven systematic approach to detect protein mistranslation in Saccharomyces Cerevisiae - James R Rosse
• Therapy driven modulation of membrane and soluble immunopeptidome in triple-negative breast cancer: implications for immunotherapy and biomarker discovery - Kirti Pandey
• Technical nuances of plasma proteomic workflows in clinical and preclinical contexts  - Samantha Emery-Corbin
• Understanding the role of peptides in direct CD8+ T cell allorecognition - Hayley Tucker
• Secretome-Driven Modulation of CD8⁺ T Cell Function in the Pancreatic Tumour Microenvironment - Ragini Bhalla
• Copper intrauterine device (IUD) use associates with metaproteomic signatures of genital inflammation, altered epithelial barrier function, and microbial dysbiosis in South African women   - Nina Radzey
• Proteomic Signatures of Noise Damage: A Comparative Study in Rat Inner Ear and Systemic Fluids - Motahare Khorrami
• Constructing region-specific nuclear map of the heart - Seyed Sadegh Eslami
• Spatial proteomics to study immune cells driving inclusion body myositis - Kael Schoffer
• Native glycomics enables true translation of observed glycans to intact glycopeptide detection - Chris Ashwood
• p53 Aggregation: Its Mechanics and Potential Contribution to the Development of Alzheimer’s Disease - David Lynch
• Hunting HERVs: Methods to map endogenous retrovirus expression in neurodegenerative disease - Dezerae Cox
• Atmospheric pressure ionization high-resolution MS histochemistry of FFPE biobanked tissue for the analysis of endogenous (neuro)peptides (as well as metabolites) aligned with today's pathology practice - Peter DEM Verhaert

Decoding Disease: From Single Cells to Immune Targets

Featuring Dr. Mark Larance and A/Prof. Pouya Faridi

Dr. Mark Larance will share how high-resolution MS and single-cell proteomics are enabling deeper insights into disease mechanisms and cellular signalling, bridging discovery research with real clinical impact. A/Prof. Pouya Faridi will present advances in clinical immunopeptidomics enabling high-depth antigen profiling and ultra-sensitive targeted assays that support precision immunotherapy development and real-time clinical decision-making.

• Presentation on statistical and computational analysis of mass spectrometry data, in particular your MSstats pipelines, which are extensively used in our community. - Olga Vitek
• RDMS.app – An online platform for the interrogation and visualisation of rare disease proteomics data. - Nikeisha J Caruana
• Visual Analytics of Immunopeptidomics and Viral Surveillance - Mitchell Jenzen
• MassSpectrum Analyzer: An interactive platform for searching parameter refinement and modification focused re-scoring - Kristian I Karlic

SoAPS DINNER AND LAWN GAMES
Date: Friday 6 February
Time: 6pm - 8pm
Location: Various - see below

Lawn Games and Pre Dinner Drink: 5pm – 6pm on the Sea Grass Lawn at Mantra Lorne
SoAPS Dinner: 6pm – 8pm at Tom’s Bar and Restaurant @ Lorne Surf Life Saving Club

Dinner and a 2 hour beverage package are included.  This event is for students and invited guests only and a ticket must be selected by attending students at the time of registration. Lanyards must be worn at all times. If you would like this added to your registration, please see the ASN staff at the registration desk.